Description
Cognitive Relax Oral Strips: L-Theanine, GABA & B6 Blend
These oral strips feature L-Theanine (from Green Tea) 50mg, GABA 25mg, and Vitamin B6 6mg in a convenient, dissolvable format. The formula is designed for those seeking relaxation support supplementation as part of their wellness routine.
L-Theanine is an amino acid found in green tea that is commonly used in formulations designed for those seeking calm focus support. GABA (gamma-aminobutyric acid) is a neurotransmitter involved in nervous system signaling. Vitamin B6 is involved in neurotransmitter synthesis and nervous system function.
Ingredients:
Green Tea L-Theanine (50 mg), GABA (25 mg), Vitamin B6 (6 mg), Pullulan (film-forming base), Mannitol, Cellulose, Strawberry Flavor, Lecithin, Malic Acid, Monk Fruit Extract (sweetener), Pectin, Erythritol, Peppermint Flavor, Steviol Glycosides (sweetener)
Product Details:
Flavor: Strawberry-Peppermint
Manufacturer Country: India
Product Amount: 30 strips / 1.2 oz / 0.07 lbs / 33 g
Gross Weight: 2 oz / 0.13 lbs / 60 g
Suggested Use:
Place one oral strip on your tongue and allow it to dissolve before swallowing. Take one oral strip anytime, up to a maximum of 1 strip per day.
Important Warnings & Cautions:
⚠️ Do not exceed recommended dose (maximum 1 strip per day)
⚠️ Pregnant or nursing mothers should consult a physician before use
⚠️ NOT intended for children under 18 years of age
⚠️ Individuals with known medical conditions MUST consult a physician before use (especially those with neurological conditions, psychiatric disorders, seizure disorders, or liver/kidney disease)
⚠️ May interact with medications – Consult healthcare provider if taking antidepressants, anti-anxiety medications, blood pressure medications, or any CNS-active drugs
⚠️ May cause drowsiness in some individuals—assess response before driving or operating machinery
⚠️ Not for those with GABA metabolism disorders or seizure disorders without medical supervision
⚠️ Contains high-dose Vitamin B6 (6mg = 353% Daily Value)—long-term high-dose B6 can cause nerve damage; not for continuous long-term use without monitoring
Storage & Safety:
⚠️ KEEP OUT OF REACH OF CHILDREN
⚠️ DO NOT USE IF SAFETY SEAL IS DAMAGED OR MISSING
⚠️ STORE IN A COOL, DRY PLACE
Understanding L-Theanine:
What is L-Theanine?
L-Theanine is an amino acid found primarily in tea leaves (especially green tea). Characteristics include:
- Crosses the blood-brain barrier
- May promote alpha brain wave activity (associated with relaxed alertness)
- Commonly paired with caffeine to "smooth out" stimulant effects
- Generally well-tolerated
This product provides 50mg L-Theanine per strip.
Typical L-Theanine doses in research:
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50-200mg for relaxation support
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200-400mg for more pronounced effects
- Often paired with caffeine in 2:1 ratio (L-Theanine:Caffeine)
50mg is on the lower end of typical supplementation doses.
Research on L-Theanine:
- Some studies suggest modest effects on subjective calmness and stress response
- Effects are subtle and vary between individuals
- Not a powerful anti-anxiety agent—effects are mild
- Generally considered safe with few side effects
Understanding GABA:
What is GABA?
GABA (gamma-aminobutyric acid) is the brain's primary inhibitory neurotransmitter—it reduces neuronal excitability and has calming effects in the central nervous system.
CRITICAL ISSUE: Oral GABA Supplementation Has Limited Evidence
The major controversy with GABA supplements:
❓ Does orally ingested GABA cross the blood-brain barrier?
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Blood-brain barrier (BBB) is a selective barrier that protects the brain
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GABA is a large, hydrophilic molecule that has difficulty crossing the BBB
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Most research suggests oral GABA does NOT significantly cross the BBB in healthy individuals
- If GABA doesn't reach the brain, it cannot directly affect CNS neurotransmission
How can GABA supplements have effects if they don't reach the brain?
Theories include:
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Peripheral effects (GABA may affect gut, vagus nerve, or peripheral nervous system)
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Placebo effect (expectation of relaxation may produce subjective calm)
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Indirect mechanisms (gut-brain axis communication)
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BBB permeability varies (some individuals or conditions may allow limited GABA passage)
Current scientific consensus: Evidence for oral GABA supplementation's effectiveness is limited and mixed. Effects, if any, are likely modest and highly variable between individuals.
This product provides 25mg GABA per strip.
Typical GABA supplement doses: 100-750mg
25mg is a LOW dose—significantly below typical supplementation amounts.
Understanding Vitamin B6:
What is Vitamin B6?
Vitamin B6 (pyridoxine) is involved in:
-
Neurotransmitter synthesis (serotonin, dopamine, GABA, norepinephrine)
- Amino acid metabolism
- Immune function
- Hemoglobin formation
This product provides 6mg Vitamin B6 per strip.
Recommended Dietary Allowance (RDA) for B6:
-
Adults 19-50: 1.3 mg/day
-
Men 51+: 1.7 mg/day
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Women 51+: 1.5 mg/day
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Pregnant women: 1.9 mg/day
-
Breastfeeding women: 2.0 mg/day
This supplement provides 6mg = 353% of Daily Value
⚠️ IMPORTANT SAFETY CONCERN: High-Dose Vitamin B6
Tolerable Upper Intake Level (UL) for B6: 100 mg/day for adults
While 6mg is below the UL, it's still HIGH compared to RDA.
Long-term high-dose Vitamin B6 supplementation (above 50mg/day for extended periods) can cause:
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Peripheral neuropathy (nerve damage causing numbness, tingling, pain in extremities)
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Photosensitivity (skin sensitivity to sunlight)
- Nausea
- Heartburn
6mg daily is unlikely to cause toxicity with short-term use, but long-term continuous use of high-dose B6 without medical supervision is not recommended.
For most people with adequate B6 intake from diet, supplementation at this dose is unnecessary.
Setting Realistic Expectations:
What This Supplement IS:
- A dietary supplement featuring L-Theanine, GABA, and Vitamin B6
- Designed for those seeking mild relaxation support
- May provide subtle calming effects in some individuals
What This Supplement is NOT:
- An anti-anxiety medication or treatment for anxiety disorders (requires medical treatment)
- A sleep aid or sedative (effects are mild)
- A treatment for stress-related medical conditions
- A substitute for stress management techniques, therapy, or medical care
- Guaranteed to produce noticeable effects (individual responses vary dramatically; some may notice nothing)
Realistic Understanding:
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Effects are SUBTLE if present at all
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L-Theanine dose (50mg) is low-moderate—effects may be minimal
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GABA (25mg) is a LOW dose and may not significantly cross blood-brain barrier
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Individual responses vary dramatically—some people notice mild effects, others notice nothing
-
Placebo effect is significant in relaxation/stress supplements
This supplement provides mild, supportive ingredients—NOT powerful anxiolytic (anti-anxiety) agents.
For clinical anxiety, panic disorder, or significant stress-related issues, professional medical and psychological treatment is necessary. Supplements cannot replace therapy or medication for diagnosed conditions.
WHO SHOULD NOT USE WITHOUT MEDICAL SUPERVISION:
Do NOT use without consulting healthcare provider if you have:
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Anxiety disorders (GAD, panic disorder, social anxiety, etc.)—requires medical treatment, not self-supplementation
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Depression or mood disorders—B6 and neurotransmitter-affecting supplements may interact with conditions or medications
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Seizure disorders or epilepsy—GABA and neurotransmitter balance are critical; supplementation requires medical supervision
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Liver or kidney disease—affects supplement metabolism
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Neurological conditions—Parkinson's, MS, neuropathy, etc.
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Psychiatric conditions—bipolar disorder, schizophrenia, etc.
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Taking psychoactive medications—antidepressants, anti-anxiety drugs, mood stabilizers, antipsychotics
Medication Interactions:
This supplement may interact with:
CNS-active medications:
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Antidepressants (SSRIs, SNRIs, tricyclics, MAOIs)—GABA and neurotransmitter effects
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Anti-anxiety medications (benzodiazepines, buspirone)—additive sedative effects
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Sleep medications—potential additive effects
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Antipsychotics—neurotransmitter interactions
-
Mood stabilizers—potential interactions
Blood pressure medications:
- GABA and L-Theanine may affect blood pressure
Levodopa (Parkinson's medication):
- Vitamin B6 can reduce levodopa effectiveness
Other medications affecting neurotransmitters or CNS function
If you take ANY medications, consult your healthcare provider before using this supplement.
Potential Side Effects:
Possible side effects may include:
L-Theanine:
- Generally well-tolerated
- Rarely: headache, dizziness, GI upset
GABA:
- Drowsiness or fatigue (in some individuals)
- Tingling sensation (paresthesia)
- Changes in heart rate or blood pressure
- Shortness of breath (rare)
- Anxiety or agitation (paradoxical in some individuals)
Vitamin B6 (high doses):
- Nausea
- Heartburn
- Photosensitivity
- Neuropathy (with long-term high-dose use)
If you experience adverse effects, discontinue use and consult healthcare provider.
Understanding Stress & Anxiety:
Important Distinction:
Occasional stress (situational, temporary) vs. Anxiety disorders (chronic, clinical conditions)
Occasional stress:
- Normal response to life challenges
- Temporary
- Managed with stress-reduction techniques, lifestyle changes, and potentially mild supplements
Anxiety disorders:
- Persistent, excessive worry or fear
- Interferes with daily functioning
- Requires professional diagnosis and treatment (therapy, medication, or both)
- Cannot be adequately treated with supplements alone
If you experience persistent anxiety, panic attacks, excessive worry, or anxiety that interferes with your life, consult a mental health professional. Supplements are not substitutes for proper mental health treatment.
Evidence-Based Stress Management:
For managing everyday stress (evidence-based approaches):
✓ Cognitive Behavioral Therapy (CBT) (gold standard for anxiety/stress management)
✓ Mindfulness meditation (proven stress reduction)
✓ Regular physical exercise (reduces stress hormones, improves mood)
✓ Adequate sleep (7-9 hours—poor sleep worsens stress response)
✓ Social connection (strong relationships buffer stress)
✓ Time management (reduce overwhelm)
✓ Deep breathing exercises (activates parasympathetic nervous system)
✓ Progressive muscle relaxation
✓ Limit caffeine and alcohol
✓ Healthy diet (nutrient deficiencies can worsen stress response)
Supplements may provide mild support but cannot replace these foundational stress management practices.
Oral Strip Delivery Considerations:
GABA & L-Theanine Absorption:
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L-Theanine is absorbed through normal digestion (small intestine)
-
GABA is absorbed through GI tract but has difficulty crossing blood-brain barrier
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Oral tissue (sublingual/buccal) absorption is limited for these compounds
-
Most absorption occurs after swallowing the dissolved strip
The oral strip format does not significantly enhance the effectiveness of these ingredients—absorption primarily occurs through normal digestive processes.
Pregnancy & Breastfeeding:
Pregnant or nursing mothers MUST consult healthcare provider before use.
Considerations:
-
L-Theanine safety during pregnancy is not well-established
-
GABA supplementation during pregnancy lacks sufficient safety data
-
High-dose Vitamin B6 during pregnancy requires medical supervision (therapeutic doses are used for morning sickness, but only under OB/GYN guidance)
-
Neurotransmitter-affecting supplements should be used cautiously during pregnancy/breastfeeding
Children & Adolescents:
This product is NOT intended for children or adolescents under 18.
Supplements affecting neurotransmitter systems should NOT be given to children without pediatrician or child psychiatrist supervision.
Long-Term Use Considerations:
Vitamin B6:
-
Long-term high-dose B6 supplementation (even at doses lower than 100mg/day) can cause peripheral neuropathy over months to years
-
If using this product regularly, monitor for symptoms of B6 toxicity (tingling, numbness, nerve pain in extremities)
-
Periodic breaks or medical monitoring recommended for long-term use
GABA & L-Theanine:
- Generally considered safe for ongoing use
- Effectiveness may diminish with continuous use (tolerance)
-
If you find yourself relying on supplements daily for stress/anxiety management, consult healthcare provider—may indicate need for professional mental health support
When to Seek Professional Help:
Consult a mental health professional (psychologist, psychiatrist, therapist) if you experience:
-
Persistent anxiety or worry (most days for 6+ months)
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Panic attacks (sudden intense fear with physical symptoms)
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Avoidance behaviors (avoiding situations due to anxiety)
- Anxiety interfering with work, relationships, or daily activities
-
Physical symptoms from anxiety (chest pain, shortness of breath, GI issues)
- Depression alongside anxiety
- Thoughts of self-harm
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Substance use to cope with anxiety or stress
Supplements cannot treat clinical anxiety disorders—professional treatment (therapy and/or medication) is necessary.
If you're experiencing a mental health crisis, contact:
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988 Suicide & Crisis Lifeline: Call or text 988
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Crisis Text Line: Text HOME to 741741
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Emergency services: 911
Disclaimer:
This product is not intended to diagnose, treat, cure, or prevent any disease.
These statements have not been evaluated by the Food and Drug Administration.
Individual results vary. This supplement features L-Theanine (50mg), GABA (25mg), and Vitamin B6 (6mg = 353% Daily Value). Effects, if any, are likely subtle and vary dramatically between individuals. Oral GABA supplementation has limited scientific support for CNS effects due to blood-brain barrier challenges. This product provides LOW doses of GABA and moderate doses of L-Theanine—effects may be minimal. This supplement is NOT a treatment for anxiety disorders, stress-related medical conditions, or mental health issues. For persistent anxiety, stress, or mental health concerns, consult a qualified mental health professional (psychologist, psychiatrist, therapist). Dietary supplements are not substitutes for professional mental health treatment, evidence-based stress management techniques, or medical care.
Long-term high-dose Vitamin B6 supplementation can cause nerve damage—if using this product regularly long-term, monitor for symptoms and consult healthcare provider.
