Description
Magnesium Glycinate Capsules
A dietary supplement providing magnesium in the glycinate form—a chelated mineral bound to the amino acid glycine. This formulation is designed for individuals seeking to address dietary magnesium inadequacy, support relaxation, and promote healthy sleep patterns. Each three-capsule serving delivers magnesium from 2,500 mg of magnesium glycinate complex.
What's In It:
• Magnesium Glycinate: A chelated form of magnesium where the mineral is bound to glycine, an inhibitory neurotransmitter amino acid. This chelation creates a compound with distinct properties:
Magnesium's Role:
- Cofactor for over 300 enzymatic reactions involving energy metabolism, protein synthesis, muscle function, nerve transmission, and blood pressure regulation
- Involved in ATP (cellular energy) production and utilization
- Regulates neurotransmitter release and nerve signal transmission
- Supports muscle relaxation by regulating calcium flux in muscle cells
- Plays a role in the hypothalamic-pituitary-adrenal (HPA) axis, which governs stress response
Glycine's Role:
- Inhibitory neurotransmitter in the central nervous system that can promote calming effects
- Activates glycine receptors, which may support relaxation and sleep quality
- When bound to magnesium, glycine may enhance absorption and reduce gastrointestinal side effects common with other magnesium forms (like magnesium oxide or sulfate)
Bioavailability Context:
Chelated magnesium forms like glycinate generally demonstrate higher absorption rates (approximately 40-50%) compared to inorganic salts like magnesium oxide (approximately 4-20%). The glycine binding protects magnesium from forming insoluble compounds in the intestines, improving uptake. Additionally, magnesium glycinate is less likely to cause the laxative effect associated with magnesium citrate or oxide.
What It Does:
This supplement addresses magnesium intake for individuals with inadequate dietary consumption. Magnesium glycinate specifically may support:
• Relaxation and Sleep: The combination of magnesium's role in neurotransmitter regulation plus glycine's calming effects may promote relaxation and improve sleep quality. Research suggests magnesium supplementation may help reduce time to fall asleep and improve sleep efficiency in those with low magnesium status.
• Stress Response: Magnesium influences the HPA axis and NMDA receptors involved in stress response. Adequate magnesium levels support the body's ability to manage physiological stress.
• Muscle Function: By regulating calcium channels and neuromuscular transmission, magnesium supports normal muscle relaxation and may help reduce muscle tension or cramping.
• Cardiovascular Support: Magnesium plays a role in vascular tone and blood pressure regulation. Adequate intake supports healthy blood pressure levels already within normal range.
Magnesium Deficiency Context:
While overt magnesium deficiency (hypomagnesemia) is relatively rare, subclinical inadequacy is common. Dietary surveys suggest 45-60% of U.S. adults consume less than the Estimated Average Requirement (EAR) for magnesium. Factors contributing to low intake include:
- Refined food consumption (processing removes magnesium)
- Reduced consumption of magnesium-rich foods (leafy greens, nuts, seeds, whole grains, legumes)
- Soil depletion affecting crop magnesium content
- Certain medications that increase magnesium excretion (diuretics, proton pump inhibitors)
- Gastrointestinal conditions affecting absorption
Who Might Benefit:
Individuals with inadequate dietary magnesium intake, those experiencing sleep difficulties, people under chronic stress, athletes (magnesium is lost through sweat), older adults (absorption decreases with age), and those taking medications that deplete magnesium.
Realistic Expectations:
Effects on sleep and relaxation may become noticeable within 1-4 weeks of consistent use, though individual responses vary. Benefits are most pronounced in those with baseline magnesium inadequacy. If dietary magnesium intake is already adequate, supplementation may not produce noticeable effects. Magnesium glycinate works by supporting physiological processes rather than providing sedative effects—it promotes natural sleep patterns rather than forcing drowsiness.
Sourcing & Production:
Manufactured in the USA.
Product Specifications:
- Servings per Container: 30 (90 capsules)
- Serving Size: 3 capsules
- Net Weight: 0.25 lb (113g)
- Country of Origin: USA
Usage Instructions: As a dietary supplement, take three (3) capsules once daily, preferably in the evening 1-2 hours before bedtime if using primarily for sleep support, or as directed by your healthcare professional. Take with food to enhance absorption and minimize any potential gastrointestinal discomfort.
Important Safety Information:
Do not exceed recommended dose. High-dose magnesium supplementation (above 350 mg elemental magnesium from supplements) may cause diarrhea in some individuals. Pregnant or nursing women, children under 18, and individuals with known medical conditions (especially kidney disease, as impaired kidney function affects magnesium excretion) should consult a physician before use.
KEEP OUT OF REACH OF CHILDREN. DO NOT USE IF SAFETY SEAL IS DAMAGED OR MISSING. STORE IN A COOL, DRY PLACE.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
